I have excatly this problem. "Directsound setpan failed" this happens when I watch something on youtube, but not always. when I leave my char for macroing, then there is no sound on youtube (sometimes). temporary solution I found is restarting windows audio(local services) via services.msc. I have sound on UO but no sound on other applications like youtube. my sound driver is up to date and have no malware detected. there is a solution below but I didnt understand. I have winows 7, can someone explain me the solution on below link ? thanks http://www.runuo.com/community/threads/directsound-setpan-failed.525859/
what headset are you using/ speakers. And have you tried a different headset/speakers? My old wireless headset was going wonky and replacing it removed that pop-up for me. can try this: right click the speaker icon in the lower right of your taskbar (by the time) select playback devices right click every one you don't normally use and select "Disable" i have 9 between all audio sources. These can get jumbled up sometimes causing errors, too.
Hey man. This fixed my problem. Been timing out on my macros for a few weeks now. Glad I found this. Thanks dude.